Basic Information
ID: ALA4121325
Type: Binding
Description: Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in HEK293F cells using substrate pretreated for 15 mins followed by substrate and [3H]-SAM addition measured after 60 mins by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4121325
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.42 | -1.44 | -1.44 |
| 344.37 | 4.41 | 4.41 |
| 501.18 | 6.22 | 6.22 |
| 484.17 | 5.54 | 5.54 |
| 309.37 | 2.07 | 2.07 |
| 356.40 | 4.27 | 4.27 |
| 340.40 | 4.57 | 4.57 |