Basic Information
ID: ALA4121334
Type: Functional
Description: Anticomplement activity in sheep erythrocytes assessed as concentration required for 50% hemolytic inhibition by classic pathway pretreated for 10 mins with guinea pig serum followed by erythrocyte addition measured after 30 mins by spectrophotometeric method
Format: BAO_0000219
Organism: Ovis aries
Cell type: Erythrocyte
Target: Erythrocyte(ALA4296518)
Document: ALA4118121
Anticomplement activity in sheep erythrocytes assessed as concentration required for 50% hemolytic inhibition by classic pathway pretreated for 10 mins with guinea pig serum followed by erythrocyte addition measured after 30 mins by spectrophotometeric method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4121334
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.19 | 1.31 | 1.31 |
| 180.16 | 1.20 | 1.20 |
| 170.12 | 0.50 | 0.50 |
| 184.15 | 0.59 | 0.59 |
| 313.35 | 2.48 | 2.48 |
| 330.25 | 1.92 | 1.92 |
| 462.36 | 0.12 | 0.12 |
| 198.17 | 0.98 | 0.98 |
| 462.36 | 0.03 | 0.03 |
| 314.34 | 2.91 | 2.91 |
| 316.22 | 1.62 | 1.62 |
| 306.23 | 0.75 | 0.75 |
| 320.25 | 1.14 | 1.14 |
| 1297.30 | ||
| 810.76 | 0.61 | 0.61 |
| 340.28 | 0.55 | 0.55 |
| 384.29 | 0.16 | 0.16 |
| 248.19 | 1.04 | 1.04 |
| 372.37 | 2.72 | 2.72 |
| 624.69 | 4.39 | 4.39 |
| 426.37 | 0.73 | 0.73 |
| 330.25 | 1.92 | 1.92 |
| 1055.85 | ||
| 356.24 | -0.31 | -0.31 |
| 412.35 | 0.64 | 0.64 |
| 465.50 | 3.73 | 3.73 |
| 624.69 | 4.77 | 4.77 |
| 364.35 | 0.60 | 0.60 |
| 324.29 | -1.20 | -1.20 |
| 956.90 | 2.58 | 2.58 |