Basic Information
ID: ALA4121347
Type: Binding
Description: Binding affinity to recombinant human RORgamma LBD (237 to 497 residues) expressed in Escherichia coli BL21 (DE3) GOLD by 1,8-ANS dye-based thermofluor assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4121347
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 643.90 | 5.81 | 5.81 |
| 596.22 | 5.95 | 5.95 |
| 598.84 | 5.22 | 5.22 |
| 569.79 | 6.07 | 6.07 |
| 614.47 | 5.65 | 5.65 |
| 568.16 | 5.26 | 5.26 |
| 558.77 | 5.06 | 5.06 |
| 584.76 | 5.15 | 5.15 |
| 628.50 | 5.58 | 5.58 |
| 587.81 | 5.48 | 5.48 |
| 551.75 | 6.11 | 6.11 |
| 620.66 | 7.14 | 7.14 |
| 603.83 | 4.94 | 4.94 |
| 584.81 | 5.40 | 5.40 |
| 615.79 | 6.10 | 6.10 |
| 623.72 | 5.91 | 5.91 |
| 613.80 | 5.12 | 5.12 |
| 592.17 | 6.10 | 6.10 |
| 595.79 | 5.90 | 5.90 |
| 602.53 | 5.89 | 5.89 |
| 593.71 | 6.50 | 6.50 |
| 646.56 | 4.56 | 4.56 |
| 577.79 | 4.64 | 4.64 |
| 591.70 | 6.26 | 6.26 |
| 555.64 | 4.65 | 4.65 |
| 566.75 | 4.92 | 4.92 |
| 589.81 | 4.69 | 4.69 |
| 629.77 | 6.05 | 6.05 |
| 597.80 | 6.15 | 6.15 |
| 601.71 | 5.62 | 5.62 |
| 604.14 | 5.80 | 5.80 |
| 583.78 | 5.76 | 5.76 |
| 597.80 | 6.10 | 6.10 |
| 615.72 | 4.45 | 4.45 |
| 611.83 | 6.35 | 6.35 |
| 557.78 | 5.66 | 5.66 |
| 569.62 | 4.82 | 4.82 |
| 602.68 | 5.76 | 5.76 |
| 606.52 | 5.16 | 5.16 |
| 634.67 | 5.19 | 5.19 |
| 615.84 | 5.03 | 5.03 |
| 595.67 | 5.13 | 5.13 |
| 602.61 | 5.91 | 5.91 |
| 605.72 | 6.65 | 6.65 |
| 508.73 | 6.87 | 6.87 |
| 613.75 | 5.51 | 5.51 |
| 605.65 | 5.28 | 5.28 |
| 667.92 | 6.89 | 6.89 |