Basic Information
ID: ALA4121351
Type: Binding
Description: Inverse agonist activity at human GAL4 DBD-fused RORbeta LBD (201 to 452 residues) expressed in HEK293T cells assessed as reduction in ROR mediated transcriptional activity after 24 hrs by dual glo luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4121351
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 596.22 | 5.95 | 5.95 |
| 584.76 | 5.15 | 5.15 |
| 628.50 | 5.58 | 5.58 |
| 587.81 | 5.48 | 5.48 |
| 551.75 | 6.11 | 6.11 |
| 620.66 | 7.14 | 7.14 |
| 603.83 | 4.94 | 4.94 |
| 615.79 | 6.10 | 6.10 |
| 623.72 | 5.91 | 5.91 |
| 595.79 | 5.90 | 5.90 |
| 593.71 | 6.50 | 6.50 |
| 591.70 | 6.26 | 6.26 |
| 566.75 | 4.92 | 4.92 |
| 589.81 | 4.69 | 4.69 |
| 629.77 | 6.05 | 6.05 |
| 597.80 | 6.15 | 6.15 |
| 583.78 | 5.76 | 5.76 |
| 602.68 | 5.76 | 5.76 |
| 595.67 | 5.13 | 5.13 |
| 605.72 | 6.65 | 6.65 |
| 613.75 | 5.51 | 5.51 |
| 605.65 | 5.28 | 5.28 |
| 667.92 | 6.89 | 6.89 |