Basic Information
ID: ALA4121353
Type: Binding
Description: Inverse agonist activity at RORgammat in human CD4 positive T cells assessed as inhibition of IL17A production in human Th17 cells after 1 hr
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4121353
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 596.22 | 5.95 | 5.95 |
| 569.79 | 6.07 | 6.07 |
| 568.16 | 5.26 | 5.26 |
| 584.76 | 5.15 | 5.15 |
| 587.81 | 5.48 | 5.48 |
| 595.79 | 5.90 | 5.90 |
| 593.71 | 6.50 | 6.50 |
| 591.70 | 6.26 | 6.26 |
| 566.75 | 4.92 | 4.92 |
| 589.81 | 4.69 | 4.69 |
| 601.71 | 5.62 | 5.62 |
| 583.78 | 5.76 | 5.76 |
| 597.80 | 6.10 | 6.10 |
| 634.67 | 5.19 | 5.19 |
| 602.61 | 5.91 | 5.91 |
| 613.75 | 5.51 | 5.51 |
| 667.92 | 6.89 | 6.89 |