Basic Information
ID: ALA4121359
Type: Binding
Description: Inverse agonist activity at RORgammat in human whole blood assessed as reduction in IL17A production
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4121359
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 643.90 | 5.81 | 5.81 |
| 596.22 | 5.95 | 5.95 |
| 569.79 | 6.07 | 6.07 |
| 568.16 | 5.26 | 5.26 |
| 584.76 | 5.15 | 5.15 |
| 587.81 | 5.48 | 5.48 |
| 551.75 | 6.11 | 6.11 |
| 584.81 | 5.40 | 5.40 |
| 595.79 | 5.90 | 5.90 |
| 593.71 | 6.50 | 6.50 |
| 646.56 | 4.56 | 4.56 |
| 591.70 | 6.26 | 6.26 |
| 589.81 | 4.69 | 4.69 |
| 629.77 | 6.05 | 6.05 |
| 601.71 | 5.62 | 5.62 |
| 604.14 | 5.80 | 5.80 |
| 583.78 | 5.76 | 5.76 |
| 597.80 | 6.10 | 6.10 |
| 615.72 | 4.45 | 4.45 |
| 569.62 | 4.82 | 4.82 |
| 606.52 | 5.16 | 5.16 |
| 634.67 | 5.19 | 5.19 |
| 615.84 | 5.03 | 5.03 |
| 595.67 | 5.13 | 5.13 |
| 602.61 | 5.91 | 5.91 |
| 508.73 | 6.87 | 6.87 |
| 613.75 | 5.51 | 5.51 |
| 605.65 | 5.28 | 5.28 |