Basic Information
ID: ALA4121745
Type: Binding
Description: Inhibition of recombinant bacterial NDM1 expressed in Escherichia coli BL21 (DE3) cells using FC5 as fluorogenic reporter substrate preincubated at 10 to 300 mins followed by substrate addition
Organism: Bacteria
Activity Charts
Bioactivity
Activity Types for Assay ALA4121745
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 279.34 | 1.97 | 1.97 |
| 297.33 | 2.11 | 2.11 |
| 394.50 | 1.31 | 1.31 |
| 445.40 | 2.47 | 2.47 |
| 410.95 | 1.82 | 1.82 |
| 309.37 | 1.98 | 1.98 |
| 358.24 | 2.73 | 2.73 |
| 198.22 | 2.18 | 2.18 |
| 214.67 | 2.70 | 2.70 |
| 259.12 | 2.80 | 2.80 |
| 306.12 | 2.65 | 2.65 |
| 198.22 | 2.18 | 2.18 |
| 259.12 | 2.80 | 2.80 |
| 168.22 | 1.74 | 1.74 |
| 283.56 | 4.00 | 4.00 |
| 479.84 | 3.13 | 3.13 |
| 180.23 | 2.04 | 2.04 |
| 249.12 | 3.35 | 3.35 |
| 394.50 | 1.31 | 1.31 |
| 216.21 | 2.32 | 2.32 |
| 249.12 | 3.35 | 3.35 |
| 280.35 | 4.35 | 4.35 |
| 234.20 | 2.46 | 2.46 |
| 430.48 | 1.58 | 1.58 |
| 455.40 | 1.93 | 1.93 |
| 445.40 | 2.47 | 2.47 |
| 405.24 | 2.58 | 2.58 |
| 348.23 | 3.28 | 3.28 |
| 404.56 | 1.78 | 1.78 |
| 313.79 | 2.63 | 2.63 |
| 376.51 | 1.17 | 1.17 |
| 236.32 | 3.26 | 3.26 |
| 182.24 | 1.61 | 1.61 |
| 412.49 | 1.44 | 1.44 |
| 293.37 | 2.28 | 2.28 |
| 297.33 | 2.11 | 2.11 |
| 249.12 | 3.35 | 3.35 |
| 232.66 | 2.83 | 2.83 |
| 390.53 | 1.47 | 1.47 |
| 333.31 | 2.39 | 2.39 |
| 382.68 | 3.93 | 3.93 |
| 307.40 | 2.59 | 2.59 |
| 320.41 | 4.79 | 4.79 |
| 331.78 | 2.76 | 2.76 |
| 358.24 | 2.73 | 2.73 |
| 445.40 | 2.47 | 2.47 |
| 210.25 | 2.05 | 2.05 |
| 348.23 | 3.28 | 3.28 |
| 428.94 | 1.96 | 1.96 |
| 194.25 | 2.35 | 2.35 |
| 315.32 | 2.25 | 2.25 |
| 455.40 | 1.93 | 1.93 |
| 208.28 | 2.66 | 2.66 |
| 463.77 | 2.96 | 2.96 |
| 406.53 | 1.18 | 1.18 |
| 335.43 | 3.19 | 3.19 |
| 348.23 | 3.28 | 3.28 |
| 502.40 | 1.77 | 1.77 |
| 432.60 | 2.38 | 2.38 |