Basic Information
ID: ALA4122223
Type: Binding
Description: Inhibition of ASIC1a in rat articular chondrocytes assessed as decrease in acid-induced intracellular calcium level at 100 uM pretreated with compound followed by acid medium stimulation in presence of voltage gated calcium channel inhibitor nimodipine after 24 hrs by Fluo-3AM dye based laser scanning confocal microscopy relative to control
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Acid-sensing ion channel 1(ALA3562170)
Document: ALA4118142
Inhibition of ASIC1a in rat articular chondrocytes assessed as decrease in acid-induced intracellular calcium level at 100 uM pretreated with compound followed by acid medium stimulation in presence of voltage gated calcium channel inhibitor nimodipine after 24 hrs by Fluo-3AM dye based laser scanning confocal microscopy relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4122223
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 229.63 | -1.08 | -1.08 |