Basic Information
ID: ALA4122263
Type: Binding
Description: Inhibition of recombinant C-terminal His10-tagged human uPA (M1 to L431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate after 15 mins by automated fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4122263
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.38 | 2.65 | 2.65 |
| 372.47 | 3.86 | 3.86 |
| 521.64 | 2.14 | 2.14 |
| 321.38 | 1.81 | 1.81 |
| 432.50 | 0.46 | 0.46 |
| 508.65 | 0.70 | 0.70 |
| 523.62 | 1.92 | 1.92 |
| 398.42 | 1.39 | 1.39 |
| 416.55 | 2.95 | 2.95 |
| 444.56 | 2.85 | 2.85 |
| 448.98 | 3.49 | 3.49 |
| 439.38 | 4.23 | 4.23 |
| 402.52 | 2.75 | 2.75 |
| 414.53 | 2.75 | 2.75 |
| 450.56 | 3.05 | 3.05 |
| 386.48 | 2.07 | 2.07 |
| 444.54 | 0.83 | 0.83 |
| 442.59 | 3.54 | 3.54 |
| 482.53 | 3.86 | 3.86 |
| 428.56 | 3.14 | 3.14 |
| 420.51 | 2.89 | 2.89 |
| 402.52 | 2.75 | 2.75 |
| 388.49 | 2.22 | 2.22 |
| 603.77 | 3.63 | 3.63 |
| 450.56 | 3.20 | 3.20 |
| 407.52 | 3.99 | 3.99 |
| 432.52 | 2.98 | 2.98 |
| 414.53 | 2.84 | 2.84 |
| 440.50 | 0.38 | 0.38 |
| 402.52 | 2.61 | 2.61 |
| 613.83 | 4.53 | 4.53 |
| 428.56 | 3.14 | 3.14 |
| 392.50 | 3.60 | 3.60 |
| 430.53 | 1.99 | 1.99 |