Basic Information
ID: ALA4122273
Type: Binding
Description: Inhibition of doxycycline induced hepsin-mediated conversion of Pro-HGF into active form in human MCF10A cells assessed as decrease in MET phosphorylation (Tyr1243/1245) at 1 to 10 uM preincubated for 30 mins followed by recombinant human pro-HGF addition measured after 30 mins by immunoblot method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4122273
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.51 | 2.94 | 2.94 |