Basic Information
ID: ALA4122274
Type: Binding
Description: Inhibition of hepsin-mediated conversion of Pro-HGF into active form in human Hs578T cells assessed as decrease in MET phosphorylation at 1 to 10 uM preincubated for 30 mins followed by recombinant human pro-HGF addition measured after 30 mins by immunoblot method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4122274
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.53 | 3.86 | 3.86 |
| 432.52 | 2.98 | 2.98 |
| 613.83 | 4.53 | 4.53 |
| 422.51 | 2.94 | 2.94 |
| 428.56 | 3.14 | 3.14 |