Basic Information
ID: ALA4122277
Type: Binding
Description: Inhibition of hepsin-mediated conversion of Pro-HGF into active form in human Hs578T cells assessed as decrease in MET phosphorylation at 100 nM preincubated for 30 mins followed by recombinant human pro-HGF addition measured after 30 mins by immunoblot method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4122277
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.35 | 5.04 | 5.04 |