Assay Report Card

Basic Information

ID: ALA4122683

Type: Binding

Description: Stabilization of c-KIT G-quadruplex DNA in imatinib-resistant human GIST48 cells harboring c-KIT V560D/D820A double mutant assessed as downregulation of c-KIT protein expression at 1 uM after 1 week by immunoblot analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
684.893.243.24