Basic Information
ID: ALA4122971
Type: Binding
Description: Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) expressed in Escherichia coli 2(DE3)pLysS Rosetta competent cells preincubated for 15 mins followed by peptide addition measured after 1 hr by luminescence-based AlphaScreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4122971
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 645.32 | 6.94 | 6.94 |
| 2254.63 | ||
| 2282.69 | ||
| 351.45 | 4.73 | 4.73 |
| 2297.72 | ||
| 759.20 | 6.30 | 6.30 |
| 479.36 | 4.45 | 4.45 |
| 379.50 | 5.34 | 5.34 |
| 521.44 | 5.48 | 5.48 |
| 2268.66 | ||
| 563.52 | 6.65 | 6.65 |
| 495.43 | 4.92 | 4.92 |
| 478.37 | 4.38 | 4.38 |
| 479.36 | 4.45 | 4.45 |
| 773.23 | 6.69 | 6.69 |
| 557.42 | 5.76 | 5.76 |
| 581.49 | 5.50 | 5.50 |
| 521.44 | 5.48 | 5.48 |