Assay Report Card

Basic Information

ID: ALA4123008

Type: Functional

Description: Cytoprotective activity against rotenone-induced cytotoxicity in human Friedreich's ataxia lymphocytes assessed as increase in cell viability at 250 to 2500 nM preincubated for 12 hrs followed by complex 1 inhibitor rotenone addition measured after 16 hrs by calceinAM ester/ethidium homodimer-1 staining based flow cytometry

Organism: Homo sapiens

Cell type: Friedreich's ataxia lymphocyte

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
319.862.502.50
565.616.576.57
621.728.138.13
481.454.234.23
649.778.918.91
593.667.357.35
635.748.528.52
733.848.458.45