Basic Information
ID: ALA4123591
Type: Binding
Description: Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Fatty acid synthase(ALA4158)
Document: ALA4118196
Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4123591
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 493.61 | 4.13 | 4.13 |
| 481.60 | 4.01 | 4.01 |
| 483.57 | 4.25 | 4.25 |
| 468.56 | 3.02 | 3.02 |
| 470.60 | 4.34 | 4.34 |
| 464.57 | 4.28 | 4.28 |
| 453.54 | 4.48 | 4.48 |
| 540.62 | 2.91 | 2.91 |
| 552.72 | 4.33 | 4.33 |
| 464.57 | 4.28 | 4.28 |
| 469.59 | 3.87 | 3.87 |
| 481.60 | 3.93 | 3.93 |
| 469.54 | 3.59 | 3.59 |
| 495.50 | 5.02 | 5.02 |
| 452.56 | 4.21 | 4.21 |
| 453.55 | 3.23 | 3.23 |
| 469.55 | 2.41 | 2.41 |
| 468.56 | 3.02 | 3.02 |
| 481.60 | 3.93 | 3.93 |
| 464.57 | 4.28 | 4.28 |
| 453.55 | 3.61 | 3.61 |
| 531.66 | 5.00 | 5.00 |
| 490.61 | 4.80 | 4.80 |
| 481.60 | 4.01 | 4.01 |
| 481.57 | 5.03 | 5.03 |
| 499.62 | 3.49 | 3.49 |
| 493.57 | 4.12 | 4.12 |
| 485.56 | 3.76 | 3.76 |
| 467.57 | 4.87 | 4.87 |
| 473.60 | 3.68 | 3.68 |
| 467.57 | 3.62 | 3.62 |
| 469.55 | 2.41 | 2.41 |
| 511.63 | 3.64 | 3.64 |
| 485.56 | 3.76 | 3.76 |
| 447.97 | 4.39 | 4.39 |
| 481.60 | 4.01 | 4.01 |
| 464.57 | 4.28 | 4.28 |
| 495.63 | 4.40 | 4.40 |
| 483.57 | 4.25 | 4.25 |
| 453.55 | 3.61 | 3.61 |
| 453.55 | 3.61 | 3.61 |
| 552.68 | 3.47 | 3.47 |
| 478.55 | 4.37 | 4.37 |
| 497.60 | 3.25 | 3.25 |
| 453.55 | 3.61 | 3.61 |
| 467.57 | 3.62 | 3.62 |