Basic Information
ID: ALA4123778
Type: Functional
Description: Antagonist activity at alpha1D adrenergic receptor in Wistar rat thoracic aorta assessed as inhibition of noradrenaline-induced contraction measured after 30 mins in presence of cocaine hydrochloride and beta-adrenoceptor blocker propranolol hydrochloride
Format: BAO_0000019
Organism: Rattus norvegicus
Strain: Wistar
Target: Alpha-1d adrenergic receptor(ALA326)
Document: ALA4118202
Antagonist activity at alpha1D adrenergic receptor in Wistar rat thoracic aorta assessed as inhibition of noradrenaline-induced contraction measured after 30 mins in presence of cocaine hydrochloride and beta-adrenoceptor blocker propranolol hydrochloride: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4123778
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.50 | 3.10 | 3.10 |
| 437.50 | 3.10 | 3.10 |
| 505.58 | 3.03 | 3.03 |
| 511.63 | 4.58 | 4.58 |
| 477.57 | 4.00 | 4.00 |
| 521.66 | 5.14 | 5.14 |
| 441.58 | 3.77 | 3.77 |
| 521.66 | 5.14 | 5.14 |
| 477.57 | 4.00 | 4.00 |
| 385.47 | 2.21 | 2.21 |
| 427.55 | 3.24 | 3.24 |
| 549.67 | 4.40 | 4.40 |
| 385.47 | 2.21 | 2.21 |