Basic Information
ID: ALA4123983
Type: ADME
Description: Inhibition of human POLRMT using 5'-FAM labelled RNA primer/DNA template duplex assessed as single nucleotide incorporation rate at 500 uM after 5 mins by SDS-PAGE analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4123983
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.16 | -1.13 | -1.13 |
| 498.17 | -2.11 | -2.11 |
| 526.15 | -2.20 | -2.20 |
| 516.16 | -1.81 | -1.81 |
| 508.16 | -2.50 | -2.50 |
| 540.18 | -1.81 | -1.81 |
| 522.19 | -2.11 | -2.11 |
| 510.15 | -1.52 | -1.52 |
| 524.18 | -1.13 | -1.13 |