Basic Information
ID: ALA4124004
Type: Binding
Description: Inhibition of MEK1/2 in EGF-stimulated human MDA-MB-231 cells assessed as reduction in pERK1/2 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: MDA-MB-231
Activity Charts
Bioactivity
Activity Types for Assay ALA4124004
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.50 | 3.12 | 3.12 |
| 392.12 | 3.55 | 3.55 |
| 482.20 | 2.47 | 2.47 |
| 474.57 | 3.94 | 3.94 |
| 393.10 | 4.15 | 4.15 |
| 461.23 | 3.50 | 3.50 |
| 561.34 | 5.15 | 5.15 |
| 406.14 | 3.58 | 3.58 |
| 448.23 | 4.93 | 4.93 |
| 248.23 | 2.81 | 2.81 |
| 349.36 | 3.24 | 3.24 |
| 267.21 | 3.55 | 3.55 |
| 420.17 | 4.20 | 4.20 |
| 439.27 | 3.56 | 3.56 |
| 489.28 | 3.86 | 3.86 |
| 230.24 | 2.67 | 2.67 |
| 477.27 | 4.09 | 4.09 |
| 407.13 | 4.17 | 4.17 |
| 331.37 | 3.10 | 3.10 |
| 406.14 | 3.81 | 3.81 |
| 407.13 | 4.24 | 4.24 |
| 421.16 | 4.26 | 4.26 |
| 420.17 | 4.15 | 4.15 |
| 266.22 | 2.95 | 2.95 |
| 295.39 | 2.82 | 2.82 |
| 249.22 | 3.41 | 3.41 |