ID: ALA4124007
Type: ADME
Description: Activation of MEK1/2 in EGF-stimulated human MDA-MB-231 cells assessed as increase in pERK1/2 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDA-MB-231
Target: Dual specificity mitogen-activated protein kinase kinase; MEK1/2(ALA2111289)
Document: ALA4118214
Activation of MEK1/2 in EGF-stimulated human MDA-MB-231 cells assessed as increase in pERK1/2 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control: 1
Bioactivity
Activity Types for Assay ALA4124007
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
489.28 | 3.86 | 3.86 |
230.24 | 2.67 | 2.67 |
331.37 | 3.10 | 3.10 |