Assay Report Card

Basic Information

ID: ALA4124007

Type: ADME

Description: Activation of MEK1/2 in EGF-stimulated human MDA-MB-231 cells assessed as increase in pERK1/2 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
489.283.863.86
230.242.672.67
331.373.103.10