Assay Report Card

Basic Information

ID: ALA4124008

Type: ADME

Description: Activation of MEK5 in EGF-stimulated human MDA-MB-231 cells assessed as increase in pERK5 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
461.233.503.50
406.143.583.58
448.234.934.93
267.213.553.55
249.223.413.41