Basic Information
ID: ALA4124008
Type: ADME
Description: Activation of MEK5 in EGF-stimulated human MDA-MB-231 cells assessed as increase in pERK5 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDA-MB-231
Target: Dual specificity mitogen-activated protein kinase kinase 5(ALA4948)
Document: ALA4118214
Activation of MEK5 in EGF-stimulated human MDA-MB-231 cells assessed as increase in pERK5 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4124008
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.23 | 3.50 | 3.50 |
| 406.14 | 3.58 | 3.58 |
| 448.23 | 4.93 | 4.93 |
| 267.21 | 3.55 | 3.55 |
| 249.22 | 3.41 | 3.41 |