ID: ALA4124009
Type: Binding
Description: Inhibition of recombinant CYP17 (unknown origin) expressed in human AD293 cells using [21-3H]17alpha-hydroxypregnenolone as substrate preincubated for 60 mins followed by substrate addition measured after 4 hrs Topcount method
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4124009
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
531.44 | 4.21 | 4.21 |
466.58 | 3.86 | 3.86 |
465.55 | 3.22 | 3.22 |
440.54 | 3.32 | 3.32 |
454.00 | 4.65 | 4.65 |
451.57 | 4.53 | 4.53 |
457.00 | 3.84 | 3.84 |
437.54 | 4.14 | 4.14 |
404.49 | 3.26 | 3.26 |
444.97 | 5.08 | 5.08 |
473.52 | 4.73 | 4.73 |
463.58 | 4.67 | 4.67 |
476.52 | 3.92 | 3.92 |
509.04 | 3.99 | 3.99 |
482.05 | 5.43 | 5.43 |
468.60 | 4.10 | 4.10 |
483.04 | 4.37 | 4.37 |
417.94 | 5.24 | 5.24 |
465.59 | 4.92 | 4.92 |
445.54 | 4.14 | 4.14 |
420.95 | 3.77 | 3.77 |
401.49 | 4.07 | 4.07 |
491.51 | 5.03 | 5.03 |
471.03 | 4.23 | 4.23 |
479.01 | 4.55 | 4.55 |
520.06 | 4.66 | 4.66 |
480.03 | 5.19 | 5.19 |
447.97 | 4.26 | 4.26 |
431.52 | 3.75 | 3.75 |
428.51 | 4.57 | 4.57 |
420.94 | 4.42 | 4.42 |
401.49 | 4.73 | 4.73 |
489.98 | 5.25 | 5.25 |
417.94 | 4.59 | 4.59 |