Basic Information
ID: ALA4124177
Type: Binding
Description: Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate phosphorylation in presence of ATP by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4124177
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 526.52 | 3.17 | 3.17 |
| 382.43 | 5.11 | 5.11 |
| 413.52 | 5.19 | 5.19 |
| 483.58 | 4.36 | 4.36 |
| 385.47 | 4.58 | 4.58 |
| 377.45 | 4.10 | 4.10 |
| 405.50 | 4.70 | 4.70 |
| 392.47 | 5.52 | 5.52 |
| 367.46 | 5.62 | 5.62 |
| 392.47 | 5.52 | 5.52 |
| 413.52 | 5.19 | 5.19 |
| 387.49 | 4.50 | 4.50 |
| 415.54 | 5.11 | 5.11 |
| 359.43 | 5.13 | 5.13 |
| 385.47 | 4.58 | 4.58 |
| 428.50 | 4.67 | 4.67 |
| 357.42 | 5.21 | 5.21 |
| 414.47 | 4.33 | 4.33 |
| 403.49 | 4.78 | 4.78 |
| 369.47 | 5.54 | 5.54 |
| 387.49 | 4.50 | 4.50 |
| 438.54 | 5.08 | 5.08 |
| 360.38 | 2.70 | 2.70 |
| 375.43 | 4.18 | 4.18 |
| 438.54 | 5.08 | 5.08 |
| 367.46 | 5.62 | 5.62 |
| 415.54 | 5.11 | 5.11 |
| 442.52 | 4.68 | 4.68 |
| 369.47 | 5.54 | 5.54 |