Basic Information
ID: ALA4124205
Type: Binding
Description: Inhibition of JAK1/TYK2 in human CD4 positive T cells assessed as inhibition of IFNalpha-stimulated STAT1 phosphorylation at Tyr-695 residue up to 1000 nM preincubated for 1 hr followed by IFNalpha stimulation measured after 30 mins by immunoblot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: JAK1/TYK2(ALA3301391)
Document: ALA4118225
Inhibition of JAK1/TYK2 in human CD4 positive T cells assessed as inhibition of IFNalpha-stimulated STAT1 phosphorylation at Tyr-695 residue up to 1000 nM preincubated for 1 hr followed by IFNalpha stimulation measured after 30 mins by immunoblot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4124205
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.52 | 3.17 | 3.17 |
| 382.43 | 5.11 | 5.11 |
| 483.58 | 4.36 | 4.36 |
| 428.50 | 4.67 | 4.67 |