Basic Information
ID: ALA4124208
Type: Binding
Description: Inhibition of JAK1/TYK2 in human CD4 positive T cells assessed as inhibition of IFNalpha-stimulated STAT1 phosphorylation at Tyr-695 residue at 1000 nM preincubated for 1 hr followed by IFNalpha stimulation measured after 30 mins by immunoblot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4124208
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.42 | 5.21 | 5.21 |