Basic Information
ID: ALA4124211
Type: Binding
Description: Inhibition of JAK1/JAK3 in human CD4 positive T cells assessed as inhibition of IL4-stimulated STAT6 phosphorylation at 300 nM preincubated for 1 hr followed by IL-4 stimulation measured after 30 mins by immunoblot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4124211
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.43 | 5.11 | 5.11 |
| 483.58 | 4.36 | 4.36 |
| 428.50 | 4.67 | 4.67 |