Basic Information
ID: ALA4124212
Type: Binding
Description: Inhibition of JAK1/JAK3 in human CD4 positive T cells assessed as inhibition of IL2-stimulated STAT5 phosphorylation at Tyr-695 residue at 50 to 100 nM preincubated for 1 hr followed by IL-2 stimulation measured after 30 mins by immunoblot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4124212
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.58 | 4.36 | 4.36 |
| 428.50 | 4.67 | 4.67 |