Basic Information
ID: ALA4124536
Type: Binding
Description: Inhibition of APN in porcine kidney microsomes using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured after 30 mins
Organism: Sus scrofa
Tissue: Kidney
Subcellular Fraction: microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4124536
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.38 | 0.53 | 0.53 |
| 374.45 | 1.61 | 1.61 |
| 466.54 | 2.62 | 2.62 |
| 374.45 | 1.35 | 1.35 |
| 385.43 | 0.92 | 0.92 |
| 385.43 | 0.92 | 0.92 |
| 386.46 | 1.71 | 1.71 |
| 439.31 | 1.81 | 1.81 |
| 429.31 | 2.35 | 2.35 |
| 410.48 | 2.20 | 2.20 |
| 429.31 | 2.35 | 2.35 |
| 439.31 | 1.81 | 1.81 |
| 404.47 | 1.62 | 1.62 |
| 390.44 | 1.05 | 1.05 |
| 404.47 | 1.44 | 1.44 |
| 375.43 | 0.63 | 0.63 |
| 404.47 | 1.44 | 1.44 |
| 374.45 | 1.24 | 1.24 |
| 450.50 | 1.07 | 1.07 |
| 420.47 | 1.06 | 1.06 |
| 394.86 | 1.70 | 1.70 |
| 394.86 | 1.70 | 1.70 |
| 439.31 | 1.81 | 1.81 |
| 390.44 | 1.05 | 1.05 |
| 414.85 | 2.03 | 2.03 |
| 405.42 | 0.95 | 0.95 |
| 436.52 | 2.64 | 2.64 |
| 390.44 | 1.05 | 1.05 |
| 360.42 | 1.05 | 1.05 |
| 410.48 | 2.20 | 2.20 |
| 466.54 | 2.62 | 2.62 |
| 375.43 | 0.63 | 0.63 |
| 404.47 | 1.44 | 1.44 |
| 420.47 | 1.06 | 1.06 |
| 374.45 | 1.35 | 1.35 |
| 394.86 | 1.70 | 1.70 |
| 405.42 | 0.95 | 0.95 |
| 374.45 | 1.35 | 1.35 |
| 360.42 | 1.05 | 1.05 |
| 405.42 | 0.95 | 0.95 |
| 361.41 | 0.44 | 0.44 |
| 388.47 | 1.66 | 1.66 |