Basic Information
ID: ALA4124668
Type: Binding
Description: Induction of CRBN ubiquitin ligase-mediated HDAC6 degradation in human MCF7 cells assessed as increase in acetylated alpha-tubulin levels at 2 uM at 2 uM preincubated for 1 hr with CRBN ligand pomalidomide followed by compound addition for 12 hrs by immunoblotting analysis
Organism: Homo sapiens
Cell type: MCF7
Activity Charts
Bioactivity
Activity Types for Assay ALA4124668
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 775.82 | 1.70 | 1.70 |