Basic Information
ID: ALA4125121
Type: Binding
Description: Inhibition of recombinant human C-terminal His10-tagged KLK7 (E23 to H252 residues) using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4125121
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.56 | 2.47 | 2.47 |
| 498.59 | 2.06 | 2.06 |
| 521.60 | 2.34 | 2.34 |
| 508.03 | 2.84 | 2.84 |
| 542.47 | 3.50 | 3.50 |
| 533.04 | 2.72 | 2.72 |
| 552.08 | 3.24 | 3.24 |
| 526.02 | 2.98 | 2.98 |
| 538.05 | 2.85 | 2.85 |
| 512.62 | 2.37 | 2.37 |
| 538.43 | 2.15 | 2.15 |
| 522.05 | 3.15 | 3.15 |
| 517.63 | 2.51 | 2.51 |
| 559.57 | 3.35 | 3.35 |
| 501.64 | 2.81 | 2.81 |
| 503.61 | 2.20 | 2.20 |
| 538.05 | 2.85 | 2.85 |
| 505.60 | 2.64 | 2.64 |
| 538.05 | 2.85 | 2.85 |