Basic Information
ID: ALA4125280
Type: Binding
Description: Inhibition of Candida albicans CYP51 assessed as reduction in [3-3H]lanosterol 14alpha-demethylation at 0.75 uM preincubated for 60 secs followed by NADPH addition measured after 60 mins by RP-HPLC analysis relative to control
Organism: Candida albicans
Activity Charts
Bioactivity
Activity Types for Assay ALA4125280
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 700.79 | 4.57 | 4.57 |
| 504.38 | 6.08 | 6.08 |
| 618.43 | 6.81 | 6.81 |
| 589.48 | 5.91 | 5.91 |
| 589.48 | 5.91 | 5.91 |
| 581.46 | 7.14 | 7.14 |
| 599.45 | 7.28 | 7.28 |
| 616.91 | 6.14 | 6.14 |
| 590.36 | 7.24 | 7.24 |
| 581.46 | 7.14 | 7.14 |
| 599.45 | 7.28 | 7.28 |
| 599.45 | 7.28 | 7.28 |
| 620.39 | 7.16 | 7.16 |
| 620.39 | 7.16 | 7.16 |
| 540.36 | 6.36 | 6.36 |
| 583.27 | 6.84 | 6.84 |
| 573.27 | 7.39 | 7.39 |