Basic Information
ID: ALA4125291
Type: ADME
Description: Hepatic clearance in Sprague-Dawley rat liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition measured up to 45 mins by LC-MS/MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4125291
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 504.38 | 6.08 | 6.08 |
| 618.43 | 6.81 | 6.81 |
| 581.46 | 7.14 | 7.14 |
| 599.45 | 7.28 | 7.28 |
| 616.91 | 6.14 | 6.14 |
| 590.36 | 7.24 | 7.24 |
| 581.46 | 7.14 | 7.14 |
| 599.45 | 7.28 | 7.28 |
| 599.45 | 7.28 | 7.28 |
| 620.39 | 7.16 | 7.16 |
| 620.39 | 7.16 | 7.16 |
| 540.36 | 6.36 | 6.36 |
| 583.27 | 6.84 | 6.84 |
| 573.27 | 7.39 | 7.39 |