Basic Information
ID: ALA4125672
Type: Binding
Description: Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta secretion at 60 mM incubated for 1 hr prior to stimulation with nigericin for 1 hr by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4125672
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 162.14 | -2.33 | -2.33 |