Basic Information
ID: ALA4125673
Type: Binding
Description: Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated processing of pro-IL-1beta to mature IL-1beta in supernatant at 150 uM incubated for 1 hr followed by nigericin addition measured after 1 hr by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4125673
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 128.13 | -0.50 | -0.50 |