Basic Information
ID: ALA4130818
Type: Binding
Description: Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell addition measured after 4 hrs by gamma counting method
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA4130818
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.66 | 4.27 | 4.27 |
| 479.56 | 5.00 | 5.00 |
| 530.46 | 6.17 | 6.17 |
| 545.56 | 5.76 | 5.76 |
| 475.60 | 5.17 | 5.17 |
| 514.00 | 5.66 | 5.66 |
| 534.64 | 5.58 | 5.58 |
| 527.57 | 5.15 | 5.15 |
| 486.58 | 4.74 | 4.74 |
| 510.04 | 5.83 | 5.83 |
| 529.57 | 5.88 | 5.88 |
| 533.63 | 5.04 | 5.04 |
| 479.56 | 5.00 | 5.00 |
| 497.55 | 5.14 | 5.14 |
| 540.46 | 5.63 | 5.63 |
| 540.46 | 5.63 | 5.63 |
| 510.59 | 6.06 | 6.06 |
| 597.56 | 6.90 | 6.90 |
| 491.59 | 4.87 | 4.87 |
| 547.56 | 6.02 | 6.02 |
| 497.55 | 5.14 | 5.14 |
| 519.60 | 4.63 | 4.63 |
| 491.59 | 4.87 | 4.87 |
| 515.54 | 5.28 | 5.28 |
| 608.46 | 6.64 | 6.64 |
| 528.62 | 5.52 | 5.52 |
| 467.60 | 4.93 | 4.93 |
| 545.56 | 5.76 | 5.76 |
| 519.60 | 4.65 | 4.65 |
| 545.56 | 5.76 | 5.76 |
| 515.54 | 5.28 | 5.28 |
| 539.66 | 4.27 | 4.27 |
| 619.36 | 6.39 | 6.39 |
| 461.57 | 4.86 | 4.86 |
| 475.60 | 5.17 | 5.17 |
| 506.57 | 4.77 | 4.77 |
| 497.55 | 5.14 | 5.14 |
| 555.69 | 5.67 | 5.67 |
| 486.58 | 4.74 | 4.74 |
| 521.62 | 4.88 | 4.88 |
| 496.01 | 5.52 | 5.52 |
| 505.58 | 4.56 | 4.56 |
| 496.01 | 5.52 | 5.52 |
| 479.56 | 5.00 | 5.00 |
| 479.56 | 5.00 | 5.00 |
| 461.49 | 5.59 | 5.59 |
| 540.46 | 5.63 | 5.63 |
| 461.57 | 4.86 | 4.86 |
| 531.99 | 5.80 | 5.80 |
| 493.59 | 5.31 | 5.31 |
| 511.58 | 5.17 | 5.17 |
| 482.61 | 4.63 | 4.63 |
| 564.01 | 6.54 | 6.54 |
| 529.57 | 5.88 | 5.88 |
| 519.60 | 4.65 | 4.65 |
| 462.56 | 4.26 | 4.26 |
| 530.46 | 6.17 | 6.17 |
| 545.56 | 5.76 | 5.76 |
| 497.55 | 5.14 | 5.14 |
| 506.57 | 4.77 | 4.77 |
| 486.58 | 4.74 | 4.74 |
| 480.55 | 4.40 | 4.40 |
| 587.46 | 5.47 | 5.47 |
| 491.59 | 4.87 | 4.87 |
| 496.56 | 5.75 | 5.75 |
| 462.56 | 4.26 | 4.26 |
| 467.60 | 4.93 | 4.93 |
| 529.57 | 5.88 | 5.88 |
| 519.60 | 4.65 | 4.65 |
| 491.59 | 4.87 | 4.87 |
| 496.01 | 5.52 | 5.52 |