Basic Information
ID: ALA4130819
Type: Binding
Description: Inhibition of perforin in human KHYG-1 cells assessed as decrease in lysis of 51Cr-labelled human K562 cells at 10 uM preincubated for 20 mins followed by addition of 51Cr-labelled human K562 cells measured after 4 hrs by gamma counting method relative to control
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA4130819
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 497.55 | 5.14 | 5.14 |
| 486.58 | 4.74 | 4.74 |
| 529.57 | 5.88 | 5.88 |
| 510.59 | 6.06 | 6.06 |
| 597.56 | 6.90 | 6.90 |
| 515.54 | 5.28 | 5.28 |
| 515.54 | 5.28 | 5.28 |
| 539.66 | 4.27 | 4.27 |
| 475.60 | 5.17 | 5.17 |
| 506.57 | 4.77 | 4.77 |
| 486.58 | 4.74 | 4.74 |
| 479.56 | 5.00 | 5.00 |
| 531.99 | 5.80 | 5.80 |
| 506.57 | 4.77 | 4.77 |
| 529.57 | 5.88 | 5.88 |