Basic Information
ID: ALA4130923
Type: Binding
Description: Inhibition of recombinant GST-tagged human JAK3 expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr by ADP-glo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4130923
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 578.69 | 5.36 | 5.36 |
| 482.54 | 6.19 | 6.19 |
| 421.46 | 4.36 | 4.36 |
| 447.50 | 4.01 | 4.01 |
| 447.50 | 4.62 | 4.62 |
| 524.60 | 5.01 | 5.01 |
| 435.49 | 4.37 | 4.37 |
| 503.56 | 5.39 | 5.39 |
| 421.46 | 5.23 | 5.23 |
| 605.62 | 8.24 | 8.24 |
| 433.47 | 4.00 | 4.00 |
| 407.43 | 4.05 | 4.05 |
| 459.51 | 4.26 | 4.26 |
| 431.50 | 5.64 | 5.64 |
| 489.53 | 5.41 | 5.41 |
| 432.48 | 5.03 | 5.03 |
| 421.46 | 4.16 | 4.16 |
| 433.47 | 4.31 | 4.31 |
| 457.53 | 6.14 | 6.14 |
| 494.55 | 5.83 | 5.83 |
| 437.52 | 5.70 | 5.70 |
| 423.48 | 4.38 | 4.38 |
| 541.66 | 5.03 | 5.03 |