Basic Information
ID: ALA4130926
Type: Binding
Description: Irreversible inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate assessed as ratio of Kinact to Ki preincubated for 2 to 60 mins followed by substrate addition measured after 1 hr by ADP-glo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4130926
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.46 | 4.36 | 4.36 |
| 447.50 | 4.01 | 4.01 |
| 524.60 | 5.01 | 5.01 |
| 421.46 | 4.16 | 4.16 |