Basic Information
ID: ALA4132847
Type: Binding
Description: Inhibition of TS/AICARFTase/GARFTase in human KB cells assessed as reduction in cell proliferation at 1 to 10 nM after 72 hrs in presence of excess of thymidine and adenosine by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Thymidylate synthase/GAR transformylase/AICAR transformylase(ALA3885528)
Document: ALA4130394
Inhibition of TS/AICARFTase/GARFTase in human KB cells assessed as reduction in cell proliferation at 1 to 10 nM after 72 hrs in presence of excess of thymidine and adenosine by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4132847
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.42 | 0.67 | 0.67 |
| 456.42 | 0.06 | 0.06 |