Basic Information
ID: ALA4132904
Type: ADME
Description: Antagonist activity at human GLUT8 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake preincubated for 5 mins followed by [3H]2-deoxy-D-glucose addition and measured after 6 mins
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Solute carrier family 2, facilitated glucose transporter member 8(ALA4295964)
Document: ALA4130400
Antagonist activity at human GLUT8 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake preincubated for 5 mins followed by [3H]2-deoxy-D-glucose addition and measured after 6 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4132904
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.55 | 5.52 | 5.52 |
| 214.27 | 2.08 | 2.08 |
| 484.57 | 5.62 | 5.62 |
| 470.54 | 5.69 | 5.69 |