Basic Information
ID: ALA4133149
Type: Binding
Description: Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 mV preincubated for 5 mins followed by ATP addition measured after 5 mins by Whole cell patch-clamp analysis
Organism: Mus musculus
Strain: Swiss
Activity Charts
Bioactivity
Activity Types for Assay ALA4133149
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 205.22 | 0.77 | 0.77 |
| 173.17 | 1.08 | 1.08 |
| 363.89 | 5.10 | 5.10 |
| 188.19 | 1.08 | 1.08 |
| 237.69 | 2.46 | 2.46 |
| 300.19 | 3.89 | 3.89 |
| 854.04 | 9.31 | 9.31 |
| 175.19 | 0.76 | 0.76 |