Basic Information
ID: ALA4133153
Type: Binding
Description: Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced current at holding potential of -60 mV preincubated for 5 mins followed by BzATP addition measured after 5 mins by Whole cell patch-clamp analysis
Organism: Mus musculus
Strain: Swiss
Activity Charts
Bioactivity
Activity Types for Assay ALA4133153
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.57 | 3.82 | 3.82 |
| 237.69 | 2.46 | 2.46 |
| 854.04 | 9.31 | 9.31 |