Basic Information
ID: ALA4133155
Type: Binding
Description: Antagonist activity at P2X7 receptor in LPS/IFNc-differentiated Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced IL-1beta release preincubated for 30 mins followed by LPS stimulation for 4 hrs using cells treated with ATP for 15 mins by ELISA
Organism: Mus musculus
Strain: Swiss
Activity Charts
Bioactivity
Activity Types for Assay ALA4133155
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.57 | 3.82 | 3.82 |
| 237.69 | 2.46 | 2.46 |