Assay Report Card

Basic Information

ID: ALA4133196

Type: Binding

Description: Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake at 750 nM preincubated for 10 mins followed by ATP addition measured after 20 mins by FLIPR assay relative to 1 mM ATP

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
854.049.319.31