Basic Information
ID: ALA4133197
Type: Binding
Description: Antagonist activity at mouse P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake at 10 uM preincubated for 10 mins followed by ATP addition measured after 20 mins by FLIPR assay relative to 1 mM ATP
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4133197
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 205.22 | 0.77 | 0.77 |
| 173.17 | 1.08 | 1.08 |
| 203.25 | 1.80 | 1.80 |
| 188.19 | 1.08 | 1.08 |
| 237.69 | 2.46 | 2.46 |
| 231.30 | 2.58 | 2.58 |
| 175.19 | 0.76 | 0.76 |