Assay Report Card

Basic Information

ID: ALA4133463

Type: Binding

Description: Induction of abnormal HSP27 dimerization in human NCI-H460 cells assessed as potentiation of 17-AAG-induced increase in cleaved caspase-7 levels at 10 uM after 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: NCI-H460

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
372.473.933.93
314.363.453.45
336.433.093.09
398.514.454.45
264.302.302.30