Assay Report Card

Basic Information

ID: ALA4133485

Type: Binding

Description: Induction of abnormal HSP27 dimerization in human NCI-H460 cells assessed as potentiation of 17-AAG-induced apoptosis by measuring necrotic cells at 10 uM after 24 hrs by Annexin V/propidium iodide double staining-based FACS analysis (Rvb = 1.42%)

Organism: Homo sapiens

Cell type: NCI-H460

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
336.433.093.09
264.302.302.30