Basic Information
ID: ALA4134037
Type: Functional
Description: Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293A cells assessed as increase in glutamate induced-calcium mobilization preincubated for 2.3 mins followed by glutamate addition measured for 1.9 mins by Fluo-4 AM dye based fluorescence assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4134037
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.77 | 3.48 | 3.48 |
| 332.36 | 3.17 | 3.17 |
| 343.33 | 3.57 | 3.57 |
| 339.37 | 3.82 | 3.82 |
| 326.33 | 2.83 | 2.83 |
| 325.34 | 3.43 | 3.43 |
| 325.34 | 3.43 | 3.43 |
| 343.33 | 3.57 | 3.57 |
| 339.37 | 3.82 | 3.82 |
| 350.35 | 3.31 | 3.31 |
| 344.32 | 2.97 | 2.97 |
| 360.77 | 3.48 | 3.48 |
| 326.33 | 2.83 | 2.83 |