Basic Information
ID: ALA4134039
Type: Functional
Description: Negative allosteric modulation of rat mGlu2 receptor expressed in HEK293 cells coexpressing Galpha15 assessed as inhibition of glutamate induced-calcium mobilization preincubated for 2.3 mins followed by glutamate addition measured for 1.9 mins by Fluo-4 AM dye based fluorescence assay
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4134039
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.33 | 2.83 | 2.83 |
| 339.37 | 3.82 | 3.82 |
| 339.37 | 3.82 | 3.82 |