Basic Information
ID: ALA4134213
Type: ADME
Description: Inhibition of recombinant human myristoylated PI3Kbeta catalytic domain expressed in Rat1 cells assessed as reduction in Akt phosphorylation at Ser47 residue after 1 hr by alpha screen Surefire assay
Organism: Homo sapiens
Cell type: Rat1
Activity Charts
Bioactivity
Activity Types for Assay ALA4134213
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 453.54 | 2.16 | 2.16 |
| 507.51 | 2.87 | 2.87 |
| 451.45 | 2.85 | 2.85 |
| 450.47 | 2.88 | 2.88 |
| 506.53 | 2.90 | 2.90 |
| 396.50 | 2.17 | 2.17 |
| 452.56 | 2.19 | 2.19 |
| 467.53 | 3.67 | 3.67 |
| 492.54 | 3.54 | 3.54 |
| 459.55 | 3.50 | 3.50 |
| 472.55 | 2.41 | 2.41 |
| 383.45 | 1.83 | 1.83 |